Need a natural pick me up? Vitamin B12 acts as an energizer, while releasing anti-stress elements throughout the body. It is well known that B12 is an integral part of treating Chronic Fatigue Syndrome. However, all patients can benefit from its energizing effects. Intramuscular B12 has been shown to be superior to taking B12 by mouth, due to its low level of gastrointestinal absorption. Monthly B12 injections are recommended and can be administered during a very short office visit.